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What is Lipase (LPS) in Blood Test? What is High and Low Lipase (LPS) Value? Causes & Treatment?

Updated: Jun 17, 2024

  • A blood lipase (LPS test is a test that measures the number of lipase in your blood.

  • Lipase is an enzyme that helps digest fats.

  • Lipase facilitates absorption by converting fats into small fatty acids and molecules such as glycerol. This allows the body to provide energy and absorb fat-soluble vitamins.

  • It is mostly produced in the pancreas. It is also produced in the stomach and salivary glands.

  • Blood lipase testing is frequently used in the diagnosis and monitoring of pancreas-related diseases or chronic diseases affecting the pancreas.

A blood lipase test is a test that measures the number of lipase in your blood.   Lipase is an enzyme that helps digest fats.   Lipase facilitates absorption by converting fats into small fatty acids and molecules such as glycerol. This allows the body to provide energy and absorb fat-soluble vitamins.   It is mostly produced in the pancreas. It is also produced in the stomach and salivary glands.   Blood lipase testing is frequently used in the diagnosis and monitoring of pancreas-related diseases or chronic diseases affecting the pancreas. The normal value of lipase in blood test  is 10 to 140 units per liter (U/L). High lipase in a blood test is a value above 140 units per liter (U/L).   If the lipase value is high in the blood test, it means that there is damage to the organs where lipase is produced intensively. Low Lipase in a blood test is a value below 10 units per liter (U/L).   Lipase is rarely found in blood. However, lipase levels below the reference value in repeated tests may mean permanent damage to the lipase-producing organs.
What is Lipase (LPS) in Blood Test? What is High and Low Lipase (LPS) Value? Causes & Treatment?

What is A Normal Lipase (LPS) Value in Blood Test ?

The normal value of lipase in blood test is 10 to 140 units per liter (U/L). Reference ranges may vary slightly between laboratories. The reference value of the laboratory where the test was performed should be taken into account.


What is High Lipase (LPS) Value in Blood Test?

  • High lipase in a blood test is a value above 140 units per liter (U/L).

  • If the lipase value is high in the blood test, it means that there is damage to the organs where lipase is produced intensively.


What Causes High Lipase (LPS) in Blood Test?

  • Pancreatic diseases (especially acute pancreatitis)

  • Chronic kidney disease

  • Ulcer

  • Gallbladder disease

  • Intestinal problems, such as intestinal obstruction

  • Diabetes

  • Salivary (salivary) gland disorders, such as infection or cancer

  • Alcohol use disorder

High Lipase (LPS) Symptoms

Symptoms vary depending on the underlying causes. But if high lipase levels originate from the pancreas, possible symptoms include:

  • Back pain

  • Nausea and vomiting

  • Diarrhea

  • Swollen or tender abdomen

  • Fever

  • Fast heart rate


How to Treat High Lipase (LPS) Level?

In order to treat high lipase, the underlying health problems that cause high lipase must first be investigated. Once the cause of high lipase is determined, your doctor will initiate the appropriate treatment protocol. Additional treatments may also be given to relieve symptoms. What you can do for high lipase: You can pay attention to your nutrition under the supervision of your doctor. Staying away from smoking and alcohol will have positive effects on your health.


What is Low Lipase (LPS) in Blood Test?

  • Low Lipase in a blood test is a value below 10 units per liter (U/L).

  • Lipase is rarely found in blood. However, lipase levels below the reference value in repeated tests may mean permanent damage to the lipase-producing organs.


What Causes Low Lipase (LPS) in Blood Test?

Some possible factors that cause low lipase include:

  • Cystic fibrosis

  • Chronic pancreatitis


Low Lipase (LPS) Symptoms

Symptoms vary depending on the underlying causes. But since low and high lipase levels generally originate from the pancreas, the following symptoms are possible.

  • Fatigue

  • Nausea

  • Diarrhea

  • Stomach ache

  • Fever

How to Treat Low Lipase (LPS) Level?

To treat low lipase, the underlying cause must first be determined. Your doctor may request additional tests for this. After the diagnosis, your doctor will implement the treatment protocol. You can speed up the healing process by staying away from smoking and alcohol and eating healthy.

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